Thursday 7 May 2015

Role of Gut Microbiome in the Regulation of Host Metabolism

Microbes are integral part of our routine life as they live in a constant association with the host to regulate the metabolism. Collection of microbes present at the epithelial surface and cavities of our body such as stomach are known as human associated microbiome/microflora. Bacteria are the predominant part of the microflora, however, some amount of virus, fungi and protozoans also present. The most complex community ever studied is the human distal gut microbiome, which contained 1,000 different microbial species across human populations. These microbes contain millions of different genes, largely more than the total number of host genes. Now a days, several research groups are working on how gut dysbiosis is related with the various metabolic disorders such as obesity, diabetes, IBD, cancer etc. This is quite interesting filed to know how microbes are interacting with each other or with the host in order to attain healthy or diseased phenotype. Since, the microflora is very complex and dynamic, and it is known to have a profound influence on the human metabolism. This vast diversity of the human-associated microbes poses a big challenge in the field of medical science. 
Recently, an interesting report published on the following topic "Modern Life Depletes Your Gut Microbes in a Number of Different Ways". 

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